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Description
This means loading up on water in the morning and early afternoon, then tapering intake in the evening

Tolessa T, Gutniak M, Holst JJ, Efendic S, Hellstrom PM
Diabetes Metabol Syndr
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology

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Diabetes 54, 2988-2994
