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Efficacy of empagliflozin as adjunctive therapy to citalopram in major depressive disorder: a randomized double-blind, placebo-controlled clinical trial

Because GLP-1 is quickly broken down by enzymes like DPP-4, only a small fraction remains active

J Diabetes Complicat

All three are prescription drugs, requiring a professional medical evaluation, a prescription from an authorized physician, and dispensing by a pharmacist

Animals All animal procedures were conducted in accordance with the guidelines of the Osaka University Animal Care and Use Committee and received approval from the committee

Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin hormone that plays a crucial role in regulating blood glucose levels and appetite