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It has been shown to have equal efficacy to that of other weak opioids such as dextropropoxyphene or codeine used alone or as co-codamol 30/5001in short-term studies of chronic pain or osteoarthritis
Can be taken anytime without the need for water or food
This article covers mechanism, clinical trial evidence, FDA-approved indications, boxed-warning safety, and the FTO, GLP1R, MC4R, and TCF7L2 variants that shape every GLP-1 response
