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Some clinical studies have shown detrimental effects of DPP-4 inhibitors on bone [13, 16, 18], with one study showing no effects [110]

But side effects are worth noting: Gastrointestinal symptoms were the most common, reported in 62% of semaglutide users compared to 42% in the placebo group

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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Selecting a selective serotonin reuptake inhibitor: clinically important distinguishing features

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