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Cardiovascular disease (CVD) is the main cause of death and disability among people with type 2 diabetes.[2] Adults with type 2 diabetes are two to four times more likely to develop CVD than adults without diabetes.[3] The FDA's decision on semaglutide is based on results from the SUSTAIN 6 cardiovascular outcomes trial (CVOT), which examined the cardiovascular safety of adding Ozempic or placebo to standard-of-care in adults with type 2 diabetes and established cardiovascular disease
GLP-1 medications can provide major health benefits, but recent studies have raised questions about a possible link with NAION, a rare optic nerve condition that can cause sudden vision loss
If separate needles are required, standard sterile multi-dose pen needles twist onto the rubber cap seamlessly
It revealed a higher affinity compared to the interaction of the individual GLP-1 and HSA-binding DARPin with the GLP-1 receptor and human serum albumin, respectively
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That is why current research focuses on improved delivery systems
