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Newer, more potent GLP-1s produce faster weight lossand faster weight loss increases hair loss risk

GLP-1 can cross the bloodbrain barrier (18) but given that it is degraded so quickly, it is unlikely that a substantial amount of active GLP-1 released from the periphery can reach the brain

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Animal research has suggested that liraglutide may also increase the risk of certain malignancies, such as thyroid cancer, but clinical studies are less definitive and continue to investigate whether these effects may also occur in humans [26]

ASMBS pediatric metabolic and bariatric surgery guidelines