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Researchers have also shown that GLP-1 receptors are present in the liver, although at much lower concentrations than in the pancreas
The key insight is that thyroid optimization must come first or alongside tirzepatide initiation, not after
According to NPR, fiber works similarly to GLP-1 drugs by keeping hunger at bay for hours
Additionally a meta-analysis found use of GLP-1RA was associated with higher risk of gallbladder and biliary disease with high doses for longer duration (113)
Some patients continue GLP-1 therapy long-term at a maintenance dose to support sustained weight loss
used liraglutide 3.0 mg daily for 32 weeks, and Jiang et al
