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This can significantly reduce its biological activity

10.1111/cns.13791 CNS Neurosci

476 If SGLT2 inhibitors and GLP-1RAs are effective in patients with heart failure (regardless of whether the ejection fraction is reduced or preserved), the commonalities between the two types of heart failure may be greater than is often thought

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It works in two main ways: In the stomach and intestines, GLP-1 slows down the process of digesting food and how fast it moves through the gut, increasing satiety

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