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Appetite suppression typically begins within the first week but becomes truly pronounced between weeks 3 and 4

Image credit: KaterynaBorodina/Shutterstock.com In a recent study published in the International Journal of Obesity , a group of researchers examined whether people experience stigma after losing or regaining weight following the use and discontinuation of glucagon-like peptide-1 receptor agonist (GLP-1RAs) medications

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Understanding Weight Regain After Stopping Semaglutide When patients discontinue semaglutide, appetite hormones gradually rebound over weeks to months

Before first use, the medication should be stored in the refrigerator