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The methyl group addition provides conformational constraint that positions critical side chains for optimal receptor interaction while maintaining sufficient flexibility for multi-receptor engagement [2] [10]

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As such, exenatide* (glucagon-like peptide-1 analogue

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2000 GLP-1 GLP-1 ,

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Tapering the Dose: Gradually reducing the dose rather than stopping abruptly to help the body adjust

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