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60 Although modest at the individual level, a 5 mm Hg SBP reduction has been associated with about a 10% lower risk of major cardiovascular events, including 13% reductions in both stroke and heart failure, 8% in ischemic heart disease, and 5% in cardiovascular death, making these effects important at a population level

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References Jastreboff AM, et al

doi: 10.1111/nmo.13738 26 AnandUYiangouYAkbarAQuickTMacQuillanAFoxMet al

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Can you comment about the fact that here we are, we're in September of 2023 and we don't even have one good clinical trial of a potential therapeutic