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Future research should focus on dedicated trials to evaluate GLP-1-RAs role in PCa management, including its potential as a prophylactic treatment and adjunct therapy in various PCa stages

IUBMB Life 75(10):856867 Mllerhj MB, Veidal SS, Thrane KT, Or D, Overgaard A, Salinas CG, Madsen MR, Pfisterer L, Vyberg M, Simon E, Broermann A, Vrang N, Jelsing J, Feigh M, Hansen HH (2022) Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH

Provincial Public Coverage: Cheapest Path Province by Province For type 2 diabetes patients, provincial drug benefit programs are the cheapest realistic path to semaglutide in Canada - coverage takes monthly cost from $250 plus down to a deductible-and-copay basis (often $0 to $40 per month for eligible seniors and low-income residents)

Prevention starts with protein intake, resistance training, micronutrient support, hydration, and gradual weight loss when medically possible

Becerril S, Fruhbeck G

Deviating from this evidence-based approach without medical justification introduces unnecessary risk without proven benefit