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The most commonly reported side effects include: Nausea Mild stomach discomfort Constipation Diarrhea Reduced appetite These symptoms are typically mild to moderate and often occur during the early stages of treatment or when increasing the dosage

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[1] It is important to understand that FDA-approved tirzepatide is supplied as a pre-filled, single-dose pen containing a sterile solution ready for injection

If your question is "can I take my tirzepatide on day five this one time because of a travel schedule," the answer is likely yes, provided 72 hours have passed, and you return to your regular weekly schedule afterward