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Interestingly, a 0.25 protective effect with a 0.95% CI of 0.160.39 was observed in patients undergoing EGD combined with colonoscopy [16]

In this review, Campbell et al

The research suggests that, while continued use may increase heart benefits over time, stopping the medication may reduce or reverse those benefits

At the index date in GLP-1 RA vs SGLT-2 inhibitor cohort, GLP-1 RA users were generally younger (median age 55 years [25-75 percentile: 45-65] vs 66 years [25-75 percentile: 57-74] more often female (59% vs 36%) and had a higher level of education compared with SGLT-2 inhibitor users (21% vs 15% were within ISCED level 6-8)