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Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome

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For the successful clinical implementation of these newly developed multiple hormone receptor agonists, it is essential to elucidate their fundamental mechanisms of action, and at the same time to confirm their efficacy and safety in real-world applications

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The most pronounced effects were observed in glial cells, the metabolic and inflammatory support system of the brain, suggesting that improving the brains environment may be as important as targeting neurons directly

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Similarly, the utility of diagnosis codes to identify falls and other risk factors for fracture is limited, and therefore differential fall patterns between the two groups may still be a cause of residual confounding

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Lancet Diabetes Endocrinol 2016

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