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GIP (Glucose-Dependent Insulinotropic Polypeptide) Receptors: Abundantly expressed in adipose (fat) tissue, the pancreas, and the central nervous system

Both medications are highly effective for weight loss, but there are some key differences: Semaglutide (Ozempic/Wegovy): Primarily acts as a GLP-1 receptor agonist and has been shown to result in around 15-18% weight loss over time for many patients

This can feel like heaviness, bloating, or aching after meals , particularly if portions consumed are large or high in fat

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These usually improve as the body adjusts, and medical supervision helps minimize risks

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