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A combined genetic score showed up to a 30% difference in HbA1c reduction be-tween low- and high-response carriers, highlighting the clinical relevance of these variants, though effects were specific to GLP-1 receptor agonists and not other drug classes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Mieczkowski M, Mrozikiewicz-Rakowska B, Kowara M, et al

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Preclinical data suggest beneficial effects on nephropathy, peripheral artery disease, and endothelial dysfunction

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