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The most common side effects (nausea, constipation, fatigue) typically diminish after the first 812 weeks

et al., The increasing rate of diabetes in Pakistan: A silent killer (2022) IDF, Prevalence of Diabetes in Pakistan (2024) Jastreboff et al., NEJM, Phase 2 obesity trial of retatrutide (2023) Reuters Next generation Lilly weight-loss drug shows added heart, liver benefits (2024) Investopedia / news20 Eli Lilly shares rise after drug helps patients lose more weight than competitors (2023) Lancet Phase 2 trial on T2DM (via ResearchGate summary) PMC meta-analysis: weight/metabolic outcomes of retatrutide Anti-obesity medication (retatrutide entry) News21 (Axios) Extraordinary promise of retatrutide (2023) USA Today (American Diabetes Association summary) News25 (NY Post) re: Phase 3 status and side effects

They did this by substituting fructose or glucose for other calories in the diet, so overall calories werent affected

Extended-Release (XR) Adderall Extended-release Adderall pills are usually in capsule shape rather than tablets

Neuropharmacology 101:98109

This potentially increases the risk of pulmonary aspiration during anaesthesia induction, where gastric contents could enter the lungs
