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These side effects may subside and then return when dosage is increased

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Once retatrutide is approved, expect a similar program to launch within 6 to 12 months

We used the Frisn staging scale to rate papilledema severity, categorizing the swelling of optic discs from stage 0 (no papilledema) to stage 5 (severe papilledema) [19]

Timeline based on typical patient experience and clinical trial data
Animal Data Dapagliflozin Dapagliflozin dosed directly to juvenile rats from postnatal day (PND) 21 until PND 90 at doses of 1, 15, or 75 mg/kg/day, increased kidney weights and increased the incidence of renal pelvic and tubular dilatations at all dose levels
