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In expanded populations, comparing semaglutide versus sitagliptin for the composite outcome of myocardial infarction or stroke yielded a hazard ratio of 0.82 (95% confidence interval (CI) 0.74 to 0.91), and comparing tirzepatide versus dulaglutide for the composite outcome including mortality yielded a hazard ratio of 0.87 (95% CI 0.75 to 1.01)

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SOURCE: Nature Medicine , Jan

[DOI] [PubMed] [Google Scholar] 68.Ryan D, Acosta A

There is also a serotonergic component

Estradiol inhibits the activation of cell death caused by ROS (209)