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If your compounding pharmacy or provider gives you a choice, consider where you are in the titration schedule

Are you refreshed or groggy

This is important because it means the weight you lose is disproportionately fat rather than muscle

However, if you have worked through the full escalation and arrived at 15 mg, you are at the dose where clinical data shows the strongest outcomes

Persistent vomiting lasting more than 24 hours or inability to keep down fluids, creating risk for dehydration, electrolyte disturbances, and acute kidney injury

Let me repeat that, zero studies looking at the impact of GLP-1 receptor agonist, and anything related to fertility or menstruation and women without PCOS, says Zaher Merhi, a reproductive endocrinologist with Rejuvenating Fertility Center and Albert Einstein College of Medicine