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Weight regain risk varies, but sustainable routines and behaviour change usually play an important role in long-term maintenance

Conclusions In this aITC, HbA1c and weight reductions were significantly greater for tirzepatide 10 and 15 mg versus semaglutide 2 mg and were similar for tirzepatide 5 mg versus semaglutide 2 mg

Fragmented tracking obscures causation when dosing, side effects, menstrual changes, and cravings overlap, and clinicians often need organized, time-stamped data over 3 months to separate drug effects from adherence or baseline variability

Weight Regain Timeline After Stopping Semaglutide Most people begin regaining weight within weeks of stopping semaglutide, with the steepest increases occurring in the first 2-3 months

GLP-13435.9%610.9% GLP-1 1