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Patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use this medication

MOTS-c is composed of 16 amino acids and has an -helical structure [14], which is the most common secondary structure in naturally-occurring proteins [19-21]

In type 2 diabetes management, metformin is typically a first-line medication

Maintaining regular meal times and avoiding prolonged periods without eating may help stabilise metabolic processes that could influence temperature regulation
