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Treatment with tirzepatide in adults with pre-diabetes and obesity or overweight resulted in sustained weight loss, and nearly 99% remained diabetes-free at 176 weeks | Eli Lilly and Company
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Semaglutide also slows stomach emptying, which may help control appetite but can contribute to digestive side effects

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Cardiovascular and renal outcomes with canagliflozin according to baseline diuretic use: a post hoc analysis from the CANVAS Program
