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Both Ozempic (semaglutide for diabetes) and Wegovy (semaglutide for weight-loss) must be kept refrigerated before use

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GLP-1 receptor agonists can trigger heartburn and reflux in some patients by slowing stomach emptying and increasing intragastric pressure

Alongside the anticipated CV safety of many of these agents, evidence for certain sodiumglucose transporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have revealed potential cardioprotective effects in patients with T2D who are at high risk of CVD events