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Semaglutide is indicated to be taken once weekly

The situations where weight loss might slow after switching include: A meaningful dose reduction (2.4 mg to 2 mg) that reduces appetite suppression enough to shift your calorie balance

Less common but more serious side effects of GLP-1 agonists include: pancreatitis, an inflammation of the pancreas that causes abdominal pain gastroparesis, in which movement of food out of the stomach is slowed or stopped bowel obstruction, a blockage that keeps food from passing through the intestines gallstone attacks and bile duct blockage

Are you tracking your thyroid levels during weight loss

doi: 10.1159/000442721 11 JaneAEpekMKlenJKunstGMaruiDRotar PavliDet al

In 2025, clinical trials increased by 46%, focusing on combination therapies and improved formulations