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Meta-analysis of human prediction error for incentives, perception, cognition, and action

Patients with certain GLP1R or GIPR variants may experience more pronounced or earlier-onset anxiety symptoms, not because the medication is unsafe, but because their baseline receptor sensitivity differs

Those with GIPR variants favoring dual-agonist response may be better candidates for tirzepatide or GLP-Squared combination therapy

10.1016/j.neurobiolaging.2010.02.014 331

The changes in fatty acid metabolism are thought to account for the improvement in hepatic insulin sensitivity and the decrease in serum triglyceride levels (48)

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