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This is why patients should always be treated by an experienced injector who truly understands the complex anatomy of the periocular region. Cypen also cautioned about the unique vascular challenges in the midface and periocular region, emphasizing the need to always withdraw the syringe slightly to check that there is no blood in it, as would be seen with penetration of the vessel wall, before injection and to inject slowly

Among these receptors, LepRb plays a critical role in mediating the effects of leptin on energy homeostasis [7]

2015 doi: 10.1111/hepr.12551

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