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In another icv-STZ rat model, exendin-4 was shown to reduce brain TNF- levels, maintain choline acetyltransferase (ChAT) activity, enhance cognitive performance, and protect hippocampal neurons from loss [101]

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Alternatively, there is evidence that fecal flora transplantation (FMT) may be effective in improving complications such as gastrointestinal dysfunction, bloating and constipation after SCI (Jing et al., 2021a)

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