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( E ) Quantification of infarct size as a percentage of the AAR on day 2 after in vivo IRI in WT ( sAC +/+ ) mice ( n = 8/group, gray bars) and sAC / littermates ( n = 89/group, white bars)

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Future studies are expected to clarify whether GLP-1 RA deserve an adjunct place in the arsenal of drugs against IBD

Although not fully clarified, the mechanism of action of GLP-1 RAs on fatty liver disease may be multifactorial

Therefore, future studies are required to determine whether pregnancy reduces maternal blood GLP-1 concentration by inhibiting GLP-1 secretion from enteroendocrine L cells, increasing GLP-1 degradation, and or expansion of maternal blood volume