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Description
Russel-Jones D, Vaag A, Schmitz O, et al

Ahrn, B., Masmiquel, L., Kumar, H., Sargin, M., Karsbl, J

Use within 30 days of first injection

Despite these promising results, the STEP-HFpEF trial did not clarify the mechanisms underlying these benefits
If you take opioids/opiates right after stopping naltrexone you may be more sensitive to them (and require lower doses) - which poses a risk of overdose

When interpreted with your qualified healthcare provider, these insights can inform whether first-line hydration and fiber strategies are likely sufficient or whether pharmacologic support may be needed sooner
