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Musculoskeletal & Anti-Inflammatory Effects GLP-1 receptors are present in: Chondrocytes Synovial tissues Macrophages Potential benefits include: Reduced inflammatory cytokines NF-B inhibition Reduced cartilage degradation Improvement in osteoarthritis inflammation The anti-inflammatory role of GLP-1 may become clinically important in rheumatologic and degenerative diseases

29 Together, these findings indicate that CD leads to more extensive and pronounced bone microstructural damage

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10.3390/pharmaceutics17081036 Pharmaceutics

Department of Health & Human Services Alex Azar , Medical Director, Weight Wellness Program, UT Southwestern Medical Center Jaime Almandoz Govind Persad, Associate Professor of Law, University of Colorado Law School Jeffrey A

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