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Retatrutide is a triple agonist (GIP/GLP-1/glucagon) currently in clinical development showing up to 24% weight loss

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In the SURMOUNT-1 trial, participants following this dosing protocol achieved mean weight reductions of 15.0% (5 mg dose), 19.5% (10 mg dose), and 20.9% (15 mg dose) at 72 weeks, compared to 3.1% with placebo

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