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The MC4R gene (rs17782313) and FTO gene (rs9939609) contribute to baseline appetite regulation and metabolic adaptation speed

In the SCALE trials, participants treated with Saxenda experienced average reductions of approximately 23 mmHg in systolic blood pressure compared with placebo

10.2337/db08-1651 [DOI] [PMC free article] [PubMed] [Google Scholar] 164.Menge BA, Tannapfel A, Belyaev O, Drescher R, Mller C, Uhl W, et al

Several studies have reported elevated GIP levels in obese humans (60, 61)

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Patients achieve best results by eating small portionstypically 1 to 1.5 cups per mealand eating slowly over 2030 minutes to allow the brain to register satiety signals