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10.1007/s00592-008-0024-0 [EL 2

While this is helpful for weight loss, it may not be ideal during breastfeeding, especially in the early weeks when energy and calorie needs are higher

Notably, a dedicated renal outcome trial showed that semaglutide reduced the risk of major kidney outcomes in patients with T2DM and established chronic kidney disease [36]

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Kang G, Leech CA, Chepurny OG, Coetzee WA, Holz GG

Yet hormonal changes can be complex: Men who begin GLP-1 therapy may initially experience a small dip in testosterone as body fat decreases, since adipose tissue helps regulate conversion of testosterone to estrogen

However, the procedure is semi-permanent, and you might observe loose skin again in around ten years or more