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Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans

Certainly with the GLP-1s coming on the market, weight loss was a nice surprise, said Sophia Thomas, doctor of nursing practice and a past president of the American Association of Nurse Practitioners

Lixisenatides effects on gastric emptying of a liquid oral glucose load has been studied after a single SC dose of 10 g per day (26) and after 8 weeks of treating with 20 g per day (27), both in inidividuals with and without T2D

doi:10.1126/science.287.5453.664 67

This leads to a degradation of matrix proteins and an activation of MMP, thereby indicating that the interaction of DPP4 and ADA might be involved in tissue remodeling (26)
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