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Semaglutides 14.9% average weight loss is substantial

10.12890/2025_005392 [DOI] [PMC free article] [PubMed] [Google Scholar] Thomsen R

Two estimands were defined: treatment policy (effect regardless of trial product discontinuation or rescue medication) and trial product (effect assuming trial product continuation without rescue medication) in randomized patients

Clinical trial outcomes reflect controlled conditions and cannot be treated as guaranteed or typical for any individual patient

Hawkes, C

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