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This careful titration is key to optimizing weight loss while keeping side effects manageable

Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models

20.8% said they went through a weight loss clinic/program

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One thing is that, in trials, some of these new medications are increasing the amount of weight loss, but that means higher reward, higher risk, with more side effects, says John Morton, MD, MPH, chief of Yale Medicine Bariatric and Minimally Invasive Surgery and a board-certified obesity medicine specialist