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In 2024, tirzepatide also gained authorization for managing moderate-to-severe obstructive sleep apnea (OSA) in obese adults (Malhotra et al., 2024)

Despite advancements in understanding and management, PH remains a substantial source of morbidity, disability, and reduced quality of life for affected individuals [48]

Tracey of the Feinstein Institutes for Medical Research for his review of the manuscript

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Switching Between Wegovy and Compounded Semaglutide for Continuous Access Wegovy supply constraints, prior authorization delays, and insurance denials have led many patients to explore compounded semaglutide as a more reliable alternative

Over time, this can lead to: Loss of lean body mass and lower resting metabolic rate Reduced protein intake , making it harder to maintain muscle Micronutrient deficiencies , particularly vitamin D, calcium, magnesium, and B-vitamins Lower energy levels and slower recovery from illness or exercise (Mozaffarian, 2025) Gastrointestinal side effects can make the picture even more complex
