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Injectables may be a better fit if maximum weight loss is your priority

Once the FDA approved Wegovy for the liver disease in August 2025 (see timeline, above) and FGF21-mimic compounds such as efruxifermin (Akero Therapeutics, now part of Novo Nordisk) began posting Phase 2b cirrhosis-reversal data at 96 weeks despite missing its primary endpoint, the specimen and assay requirements changed in lockstep

Research on NAD+ supplementation, usually through precursors like NMN or NR, suggests potential benefits for anti-aging and cellular health

In addition to its role in treating type 2 diabetes, Ozempic is also approved for use in individuals with type 2 diabetes who also have cardiovascular disease or chronic kidney disease, helping to reduce associated risks