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According to Pfizer, the enzymes returned to normal after the patient ceased taking danuglipron
At this point a glucose test will show abnormal blood sugar levels, which are not yet high enough to cause symptoms
[22] [23] This mechanism improves glycemic control with a low risk of hypoglycemia when used alone, though the risk increases when combined with insulin or sulfonylureas
Another priority will be the development of reliable non-invasive biomarkers to track changes in liver fat content and fibrosis, which could include circulating markers like cytokeratin-18 fragments or scoring systems like fibrosis-4 (FIB-4) score and enhanced liver fibrosis (ELF) test, in addition to imaging-based assessments in patients with MASLD [37, 38]
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