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The clinical trial lasted for 68 weeks, with participants receiving either a weekly injection of semaglutide or a placebo

Weight Loss Plateau on Semaglutide Semaglutide (Wegovy) produces an average of 14.9% body weight loss at 68 weeks on the 2.4mg maximum dose, per the STEP 1 trial (Wilding et al., NEJM 2021)
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In a 52-week randomized, double-blind, placebo-controlled phase 2 trial involving 64 adults at high fracture risk (due to low BMD or recent fragility fractures), participants received once-weekly semaglutide (1.0 mg) or placebo
