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1994;60:421424 9 Plant extracts for the topical management of psoriasis: a systematic review and meta-analysis

67,68 Dulaglutide and liraglutide also provide notable reductions, with HbA1c decreases of 1.0% to 1.5% and weight loss of 24% of total body weight

3.7 Cancer risk by individual GLP-1 RA compound When stratified by individual GLP-1 RAs, liraglutide and semaglutide were associated with reduced risk of gastrointestinal cancers (HR 0.77 and 0.79, respectively), while dulaglutide showed a neutral association (HR 0.91, 95% CI: 0.721.14)

Nobody has studied normal-weight women on these drugs and tracked their cancer outcomes

The correlation between inflammation and GLP-1 level is complicated: it was shown that endogen GLP-1 is elevated in inflammatory settings, such as critically ill patients or after cardiac surgery

Additional well-designed, prospective studies are needed to confirm the potential benefit of GLP-1 receptor agonist treatment for patients with advanced CKD or ESKD." For further information: DOI: 10.1001/jamanetworkopen.2022.1169 Keywords: CKD, ESKD, GLP-1 receptor agonist, DPP-4 inhibitors, type 2 diabetes, JAMA Network Open, chronic kidney disease, end-stage kidney disease, National Health Insurance Research Database of Taiwan, MACCE, Mortality rate