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On average, semaglutide GLP-1 injections achieve a 15% reduction in starting weight when used as part of a comprehensive weight loss plan

In a recent meta-analysis of 12 observational studies of patients with T2DM treated with either SGLT2 inhibitors or GLP-1RAs, the GLP-1RA group exhibited a significantly lower relative risk of lower limb amputation vs the SGLT2 inhibitor cohort (3.54 vs 4.72 events per 1000 patient-years).37 Furthermore, in the CANVAS program involving 10,142 patients with T2DM at high cardiovascular risk, canagliflozin was found to be associated with a 1.97-fold increased risk of lower-limb amputations

High-profile GLP-1s Dr Kieran Seyan, chief medical officer at Lloyds Pharmacy Online Doctor, said, It's unusual for a prescription medicine to have such a high public profile outside of a clinical setting, as we are seeing with GLP-1 medicines

Some focus on convenience

Your doctor will tell you about hypoglycemia symptoms to look out for

And so another key thing to consider when we're on a GLP-1 is that if we're not eating much, if we're not careful, we might not be getting the vitamins and minerals that our body needs