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The results indicated that the solanezumab-treated group had greater cognitive decline on some measures relative to placebo, and that solanezumab treatment did not exert any beneficial effects on downstream biomarkers, whereas gantenerumab significantly reduced amyloid plaques, CSF total tau, and phospho-tau181 and attenuated increases in neurofilament light chain [53]

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A neuroimaging study suggested that depression strongly leads to memory dysfunction given that morphological changes in the brain of depressed patients, such as atrophy and abnormal alteration of the frontal cortex, thalamus, and hippocampus, is related to cognitive impairment (Zhang et al., 2016)

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[12] Fortunately, no congenital abnormalities in humans have been directly linked to biotin deficiency, and ensuring an adequate intake (through diet or a prenatal vitamin) appears to maintain normal pregnancy outcomes

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313918) probes were purchased from Advanced Cell Diagnostics

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doi: 10.2337/dc10-1949

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Prioritize nutrition: Focus on nutrient-dense foods during eating windows

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