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Semaglutides influence on hormonal pathways may lead to a reduction in androgen levels, addressing these symptoms and improving the quality of life for individuals with PCOS

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Study 8 was a 72-week trial that enrolled 1,407 patients with obesity (BMI greater than or equal to 30 kg/m2), patients with type 2 diabetes mellitus were excluded

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however, in a subgroup of 48 participants with baseline flow-mediated dilation of 3% or greater (healthy flow-mediated dilation is around 7%), 614 hesperidin mitigated the negative effect of a high-fat meal on endothelial function