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The real-world condition included all patients from the ideal condition and those who exhibited limited adherence, with missing 12-month weight values conservatively imputed using a baseline observation carried forward approach

Semaglutide has helped millions achieve significant weight loss by slowing stomach emptying and signaling satiety in the brain

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However, clinical data suggests tirzepatide may produce greater average weight loss, which could mean shorter treatment duration

In an advanced stage with lymphatic or other spread, chemoradiation may be added

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