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Combination treatment of leptin with other drugs The limited efficacy of leptin monotherapy in treating obesity, largely due to leptin resistance, has prompted investigations into combination therapies that enhance leptins effectiveness by targeting complementary pathways or mitigating resistance mechanisms

The steatotic liver disease burden paradox: unraveling the key role of alcohol

When this mucus migrates away from the epithelial surface, it undergoes proteolytic and glycosidic degradation, leading to expansion of the mucin network and the formation of a looser, more permeable outer mucus layer (5)

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BMJ 2023