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Because pancreatin degradation assays are relevant to predict the stability of peptides in the gastrointestinal tract 52 , our data thus suggest that hybrid 24 could be suitable for oral administration and the peptide/oligourea hybrid approach reported here would be used to improve pharmacokinetic properties of some peptide-based drugs

Although the expression of GLP-1R in liver tissue is controversial, GLP-1RAs have been shown to act as regulatory pathways affecting metabolic disorders

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While all of these potential benefits are exciting, experts said they need much more study, and even then, whether they might ever be utilized as a treatment for schizophrenia, for example, would depend on a number of factors: how much and how consistently they work, as well as how they compare to treatments that are already available

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Aksoy D., Solmaz V., Cavusoglu T., Meral A., Ates U., Erbas O

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