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These findings place GLP-1 receptor agonists among the most effective pharmacological strategies currently available for reducing cardiometabolic and renal risk in high-risk populations

I think we see that with all GLP-1 drugs

Neuropharmacology, 149(February), 124132

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Exendin-4 shares approximately 53% structural similarity with human GLP-1 but is resistant to DPP-4 enzyme degradation, giving it a significantly longer half-life than native human GLP-1, which breaks down in approximately 2 minutes

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